KidsCalc - Ganciclovir

IV Ganciclovir area under the curve calculator for children aged 1 month to 18 years

Dose records (mg)

Date	Hour	Minute	Dose (mg)	Infusion time (h)

Ganciclovir level (mg/L)

Date	Hour	Minute	Conc (mg/L)

Weight (kg)

Creatinine level (micromol/L)

Instructions:

Dose records (mg): Please enter the 3 most recent doses

Hour: Please use the 24-hour format enter an integer between 0 and 23

Minute: Please enter an integer between 0 and 59

Infusion time (h): Please enter the infusion time

(x.xx hours)

Conc (mg/L): Please enter the peak (1-4 hours after

the dose) and

trough (< 1 hour prior to the

next dose)

ganciclovir level

(x.x mg/L)

Please fill in all fields and press calculate to see the result.

Intended use statement

The ‘IV Ganciclovir area under the curve calculator for children aged 1 month to 18 years’ uses an individual’s age, weight, serum creatinine, trough concentration at steady state, dose, and dosing interval to predict the 24-hour area under the concentration-time curve (AUC₂₄).

This calculator is based on a population pharmacokinetic model. (Yang et al, Antimicrob Agents Chemother 2024;68(10):e0052524)

This calculator is intended for use in children aged 1 month to 18 years with a weight > 5 kg.

It has not been validated in children:

with renal impairment with eGFR < 25 mL/min/1.73m²
receiving extracorporeal membrane oxygenation, or renal replacement therapy